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Research Publications

Published research using PolyPico microdispensing and contactless liquid handling technology.

Bioprinting / Cell dispensing

Albumin Reprograms the B cell Transcriptional Landscape and Improves Neutrophil Antimicrobial Function in Patients with Decompensated Cirrhosis

Joan Clària 1,2,3,4,‡ [email protected] ∙ Ferran Aguilar 1,‡ ∙ Juan-José Lozano 3,‡ ∙ Laura Jiménez-Gracia 4,5,‡ ∙ Juan C. Nieto 4,5,‡ ∙ Berta Romero-Grimaldo 1,2,3 ∙ Xavi Marcos-Fa 6 ∙ Emma Giarracco 6 ∙ Emmanuel Weiss 1,7,8 ∙ Jonel Trebicka 1,9 ∙ Inmaculada Hernàndez 4,5,10 ∙ Javier Fernandez 1,2 ∙ Mireia Casulleras 1,2 ∙ Cristina López-Vicario 1,2,3 ∙ Sinan Muldur 11 ∙ Alex Hopke 11 ∙ Alexandru Vlagea 2 ∙ Ana M. Aransay 3,12 ∙ Domenica Marchese 4,5 ∙ Mauro Bernardi 13 ∙ Rajiv Jalan 1,14 ∙ Paolo Angeli 1,15 ∙ Giuliana Magri 16 ∙ Andrea Cerutti 6,17 ∙ Daniel Irimia 11 ∙ Holger Heyn 4,5,† ∙ Vicente Arroyo 1,† ∙ Richard Moreau 1,7,18

Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming

Evelyn Strickland 1 2, Deng Pan 3, Christian Godfrey 4 5, Julia S. Kim 1, Alex Hopke 4 5 6, Wencheng Ji 7, Maureen Degrange 8, Bryant Villavicencio 9, Michael K. Mansour 5 10, Christa S. Zerbe 11, Daniel Irimia 4 5 6, Ariel Amir 3 7, Orion D. Weiner 1 2 12

BTK inhibitor–induced defects in human neutrophil effector activity against Aspergillus fumigatus are restored by TNF-α

Diego A. Vargas-Blanco,1,2 Olivia W. Hepworth,1,2 Kyle J. Basham,1 Patricia Simaku,1 Arianne J. Crossen,1 Kyle D. Timmer,1 Alex Hopke,2,3,4 Hannah Brown Harding,1,2 Steven R. Vandal,5 Kirstine N. Jensen,1,2 Daniel J. Floyd,1 Jennifer L. Reedy,1,2 Christopher Reardon,1 Michael K. Mansour,1,2 Rebecca A. Ward,1 Daniel Irimia,2,3,4 Jeremy S. Abramson,6 and Jatin M. Vyas1,2

Authorship note: DAVB and OWH are co–first authors.

Published May 7, 2024

Ex Vivo Human Neutrophil Swarming Against Live Microbial Targets

Alex Hopke, Daniel Irimia

Neutrophil, Methods and Protocols (Book); Editors: Mark T. Quinn, Frank R. DeLeo; Pages 107-116 | ISBN: 978-1-0716-0154-9

Chemotaxis and swarming in differentiated HL‑60 neutrophil‑like cells

Kehinde Adebayo Babatunde, Xiao Wang, Alex Hopke, Nils Lannes, Pierre‑Yves Mantel & Daniel Irimia

Nature Scientific Reports 11, 778 (2021)

Additive manufacturing / Manufacturing

Ultrashort laser sintering of printed silver nanoparticles on thin, flexible, and porous substrates

Ayesha Sharif, Nazar Farid, Peter McGlynn, Mingqing Wang, Rajani K Vijayaraghavan, Asim Jilani, Gabriel Leen, Patrick J McNally and Gerard M O’Connor

Journal of Physics D: Applied Physics, Volume 56, Number 7 2023 DOI 10.1088/1361-6463/acb367

Additive manufacturing: scientific and technological challenges, market uptake and opportunities

Syed A.M. Tofail, Elias P. Koumoulos, Amit Bandyopadhyay, Susmita Bose, Lisa O’Donoghue, and Costas Charitidis

Materials Today, Volume 21, Issue 1, January–February 2018, Pages 22-37

Protein Crystallography

Pico-litre Sample Introduction and Acoustic Levitation Systems for Time Resolved Protein Crystallography Experiments at XFELS

Peter Docker, Robert Morris, Michael Newton, Elizabeth Dye, James Kay, John Beale, Danny Axford, Allen Orville, Dave Stuart and Gabriel Leen

Sensors & Transducers, Vol. 214, Issue 7, July 2017, pp. 39-45

Tractor beam acoustic levitation for time resolved crystallography experiments

V Baker, F Gueniat, D Axford, P Aller, N Baker, G Leen, P Docker

14th International Conference on Synchrotron Radiation Instrumentation (SRI 2021) Journal of Physics: Conference Series 2380 (2022) 012112 doi:10.1088/1742-6596/2380/1/012112

An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography

Agata Butryn, Philipp S. Simon, Pierre Aller, Philip Hinchliffe, Ramzi N. Massad, Gabriel Leen, Catherine L. Tooke, Isabel Bogacz, In-Sik Kim, Asmit Bhowmick, Aaron S. Brewster, Nicholas E. Devenish, Jürgen Brem, Jos J. A. G. Kamps, Pauline A. Lang, Patrick Rabe, Danny Axford, John H. Beale, Bradley Davy, Ali Ebrahim, Julien Orlans, Selina L. S. Storm, Tiankun Zhou, Shigeki Owada, Rie Tanaka, Kensuke Tono, Gwyndaf Evans, Robin L. Owen, Frances A. Houle, Nicholas K. Sauter, Christopher J. Schofield, James Spencer, Vittal K. Yachandra, Junko Yano, Jan F. Kern & Allen M. Orville.

NATURE COMMUNICATIONS (2021) 12:446

Hydrogel printing

Arrays of 3D double-network hydrogels for the high-throughput discovery of materials with enhanced physical and biological properties

Cairnan Duffy, Andrea Venturato, Anthony Callanan, Annamaria Lilienkampf, Mark Bradley

Acta Biomaterialia Volume 34, 1 April 2016, Pages 104-112

Bio-Sensors

A New Pico-Litre Fluid Dispensing Technology for New Possibilities

A New Pico-Litre Fluid Dispensing Technology for New Possibilities

G. Leen

Biosensors Journal, Volume 5, Issue 1, 2016

Additional Published / Media References

NUI Galway and start-up Morrigan Dynamics aim to use process to grow tissues for transplants

Michel Destrade, Wed Aug 27 2014

The Irish Times

Digital Manufacturing: The Industrialization of “Art to Part” 3D Additive Printing

Chandrakant D. Patel, Chun-Hsien Chen

ISBN:9780323950633, Elsevier Science 2022, Page 166

Devices and Systems for Laboratory Automation

By Kerstin Thurow, Steffen Junginger

Wiley 2022, ISBN:9783527348329, 3527348328, Page 176

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