Research Publications
Published research using PolyPico microdispensing and contactless liquid handling technology.
Bioprinting / Cell dispensing
Albumin Reprograms the B cell Transcriptional Landscape and Improves Neutrophil Antimicrobial Function in Patients with Decompensated Cirrhosis
Joan Clària 1,2,3,4,‡ [email protected] ∙ Ferran Aguilar 1,‡ ∙ Juan-José Lozano 3,‡ ∙ Laura Jiménez-Gracia 4,5,‡ ∙ Juan C. Nieto 4,5,‡ ∙ Berta Romero-Grimaldo 1,2,3 ∙ Xavi Marcos-Fa 6 ∙ Emma Giarracco 6 ∙ Emmanuel Weiss 1,7,8 ∙ Jonel Trebicka 1,9 ∙ Inmaculada Hernàndez 4,5,10 ∙ Javier Fernandez 1,2 ∙ Mireia Casulleras 1,2 ∙ Cristina López-Vicario 1,2,3 ∙ Sinan Muldur 11 ∙ Alex Hopke 11 ∙ Alexandru Vlagea 2 ∙ Ana M. Aransay 3,12 ∙ Domenica Marchese 4,5 ∙ Mauro Bernardi 13 ∙ Rajiv Jalan 1,14 ∙ Paolo Angeli 1,15 ∙ Giuliana Magri 16 ∙ Andrea Cerutti 6,17 ∙ Daniel Irimia 11 ∙ Holger Heyn 4,5,† ∙ Vicente Arroyo 1,† ∙ Richard Moreau 1,7,18
Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming
Evelyn Strickland 1 2, Deng Pan 3, Christian Godfrey 4 5, Julia S. Kim 1, Alex Hopke 4 5 6, Wencheng Ji 7, Maureen Degrange 8, Bryant Villavicencio 9, Michael K. Mansour 5 10, Christa S. Zerbe 11, Daniel Irimia 4 5 6, Ariel Amir 3 7, Orion D. Weiner 1 2 12
BTK inhibitor–induced defects in human neutrophil effector activity against Aspergillus fumigatus are restored by TNF-α
Diego A. Vargas-Blanco,1,2 Olivia W. Hepworth,1,2 Kyle J. Basham,1 Patricia Simaku,1 Arianne J. Crossen,1 Kyle D. Timmer,1 Alex Hopke,2,3,4 Hannah Brown Harding,1,2 Steven R. Vandal,5 Kirstine N. Jensen,1,2 Daniel J. Floyd,1 Jennifer L. Reedy,1,2 Christopher Reardon,1 Michael K. Mansour,1,2 Rebecca A. Ward,1 Daniel Irimia,2,3,4 Jeremy S. Abramson,6 and Jatin M. Vyas1,2
Authorship note: DAVB and OWH are co–first authors.
Published May 7, 2024
Ex Vivo Human Neutrophil Swarming Against Live Microbial Targets
Alex Hopke, Daniel Irimia
Neutrophil, Methods and Protocols (Book); Editors: Mark T. Quinn, Frank R. DeLeo; Pages 107-116 | ISBN: 978-1-0716-0154-9
Chemotaxis and swarming in differentiated HL‑60 neutrophil‑like cells
Kehinde Adebayo Babatunde, Xiao Wang, Alex Hopke, Nils Lannes, Pierre‑Yves Mantel & Daniel Irimia
Nature Scientific Reports 11, 778 (2021)
Additive manufacturing / Manufacturing
Ultrashort laser sintering of printed silver nanoparticles on thin, flexible, and porous substrates
Ayesha Sharif, Nazar Farid, Peter McGlynn, Mingqing Wang, Rajani K Vijayaraghavan, Asim Jilani, Gabriel Leen, Patrick J McNally and Gerard M O’Connor
Journal of Physics D: Applied Physics, Volume 56, Number 7 2023 DOI 10.1088/1361-6463/acb367
Additive manufacturing: scientific and technological challenges, market uptake and opportunities
Syed A.M. Tofail, Elias P. Koumoulos, Amit Bandyopadhyay, Susmita Bose, Lisa O’Donoghue, and Costas Charitidis
Materials Today, Volume 21, Issue 1, January–February 2018, Pages 22-37
Protein Crystallography
Pico-litre Sample Introduction and Acoustic Levitation Systems for Time Resolved Protein Crystallography Experiments at XFELS
Peter Docker, Robert Morris, Michael Newton, Elizabeth Dye, James Kay, John Beale, Danny Axford, Allen Orville, Dave Stuart and Gabriel Leen
Sensors & Transducers, Vol. 214, Issue 7, July 2017, pp. 39-45
Tractor beam acoustic levitation for time resolved crystallography experiments
V Baker, F Gueniat, D Axford, P Aller, N Baker, G Leen, P Docker
14th International Conference on Synchrotron Radiation Instrumentation (SRI 2021) Journal of Physics: Conference Series 2380 (2022) 012112 doi:10.1088/1742-6596/2380/1/012112
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
Agata Butryn, Philipp S. Simon, Pierre Aller, Philip Hinchliffe, Ramzi N. Massad, Gabriel Leen, Catherine L. Tooke, Isabel Bogacz, In-Sik Kim, Asmit Bhowmick, Aaron S. Brewster, Nicholas E. Devenish, Jürgen Brem, Jos J. A. G. Kamps, Pauline A. Lang, Patrick Rabe, Danny Axford, John H. Beale, Bradley Davy, Ali Ebrahim, Julien Orlans, Selina L. S. Storm, Tiankun Zhou, Shigeki Owada, Rie Tanaka, Kensuke Tono, Gwyndaf Evans, Robin L. Owen, Frances A. Houle, Nicholas K. Sauter, Christopher J. Schofield, James Spencer, Vittal K. Yachandra, Junko Yano, Jan F. Kern & Allen M. Orville.
NATURE COMMUNICATIONS (2021) 12:446
Hydrogel printing
Arrays of 3D double-network hydrogels for the high-throughput discovery of materials with enhanced physical and biological properties
Cairnan Duffy, Andrea Venturato, Anthony Callanan, Annamaria Lilienkampf, Mark Bradley
Acta Biomaterialia Volume 34, 1 April 2016, Pages 104-112
Bio-Sensors
A New Pico-Litre Fluid Dispensing Technology for New Possibilities
A New Pico-Litre Fluid Dispensing Technology for New Possibilities
G. Leen
Biosensors Journal, Volume 5, Issue 1, 2016
Additional Published / Media References
NUI Galway and start-up Morrigan Dynamics aim to use process to grow tissues for transplants
Michel Destrade, Wed Aug 27 2014
The Irish Times
Digital Manufacturing: The Industrialization of “Art to Part” 3D Additive Printing
Chandrakant D. Patel, Chun-Hsien Chen
ISBN:9780323950633, Elsevier Science 2022, Page 166
Devices and Systems for Laboratory Automation
By Kerstin Thurow, Steffen Junginger
Wiley 2022, ISBN:9783527348329, 3527348328, Page 176
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